Wednesday, July 26, 2017

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PHSANZ PHT Registry Update.
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PHSANZ PHT Registry Update

Registry records as at October 2015
Users = 81
Patients = 2973
Medications = 14013
6MWT = 17351
RHC = 5154
ECHO = 16657
PFT = 6893
Hospital Events = 4090
Surveys = 833
Physicians = 65

Registry Highlights

  • n = 2,672 clean patients – largest per capita in the world
     

  • Annualised rate of death according to etiology ranging from 8.6% for iPAH to 24.9% for PAHResp
     

  • Median survival all cause PHT 6.5yrs - Respiratory related PHT, left heart disease and scleroderma statistically significant highest mortality
     

  • Significant mortality variance by centre which probably reflects the mix of patients being treated
     

  • A survival benefit for first initiation of bosentan and ambrisentan over sildenafil as monotherapy

In 2016:
  • More analysis on medications to be done
  • Explore less frequent diagnoses e.g, portopulmonary
  • Delta change in parameters with treatment
Download the full Registry Report PDF by Clicking Here
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